Cycloastragenol98 is extract from the legumes Mongolia astragalus dried roots or hydrolysis from the Astragaloside IV.
Cycloastragenol 98 can enhanced immunity, scavenging free radicals, protecting cardiac cells, enhance myocardial viability, relieve myocardial ischemia, anti-heart failure and so on. The mechanism is that by inhibiting phosphodiesterase activity, cyclic adenosine monophosphate (cAMP) decomposition to reduce, the increase of cAMP concentration in myocardial cells, promote the release of calcium ions in sarcoplasmic reticulum. Astragalus also improves blood rheology, reduce blood viscosity, and reduce cardiac stress. In China many years of clinical application of Chinese medicine " Astragalus Liquid," TCM injections "Huangqi injections" ,the main ingredient is Astragaloside Ⅳ, " Huangqi injections " is mainly used for the treatment of viral myocarditis, heart failure and hepatitis and other diseases . “Astragalus Liquid" is mainly used for the treatment of viral hepatitis, and improves immunity, anti- fatigue. In 2009 Nobel Prize in Physiology or Medicine was awarded three American scientists Elizabeth Blackburn , Carol Greider and Jack Szostak , in recognition of their "discovery of telomeres and telomerase is how chromosomes are protected ." Telomere shortening may be the cause of aging and the cause of induced bone marrow, lung and skin lesions. If telomere length is maintained, it can delay cell senescence. Recently, the mechanism of Cycloastragenol 98 research has been a breakthrough. Especially the U.S. biotechnology company Geron discovered cycloastragenol 98 mainly by activating telomerase and exert their biological effects. It has played a positive impetus effect on the study of the Cycloastragenol 98 as new drugs and health products development.